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Clinical Pharmacology of Antihypertensive Drugs

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Hypertension and Cardiovascular Disease in Asia

Part of the book series: Updates in Hypertension and Cardiovascular Protection ((UHCP))

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Abstract

This chapter describes the pharmacological classes of antihypertensive drugs regarding their mechanisms of action and side effects. The mechanism of action is analyzed through a pharmacological approach, including the molecular receptor targets, the various sites along the arterial system, and the extra-arterial sites of action. Side effects are described and explained through their pharmacological mechanisms. Although several antihypertensive drugs are available, new agents continue to be introduced, thus increasing the spectrum of drug therapy for hypertension. A new novel class of antihypertensive drugs targeting brain renin–angiotensin system is mentioned in this chapter.

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Author information

Authors and Affiliations

  1. Department of Internal Medicine, College of Medicine, Chungbuk National University, Cheongju, South Korea

    Myeong-Chan Cho

  2. Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, Seoul, South Korea

    Ki Chul Sung

  3. Division of Cardiology, Department of Internal Medicine, Yeouido St. Mary’s Hospital, Catholic University, Seoul, South Korea

    Eun Joo Cho

  4. Division of Cardiology, Department of Internal Medicine, Hanyang University Hospital, Seoul, South Korea

    Jinho Shin

Authors
  1. Myeong-Chan Cho
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  2. Ki Chul Sung
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  3. Eun Joo Cho
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  4. Jinho Shin
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Corresponding author

Correspondence to Myeong-Chan Cho .

Editor information

Editors and Affiliations

  1. Apollo Hospitals, Apollo Institute for Blood Pressure Management, Hyderabad, India

    C. Venkata S. Ram

  2. Head, Division of Nephrology Department of Medicine, Yong Loo Lin Sch of Med Natl Univ of Sin, Singapore, Singapore

    Boon Wee Jimmy Teo

  3. Department of Cardiology, Hero DMC Heart Institute, Dayanand Medical College, Ludhiana, Punjab, India

    Gurpreet S. Wander

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Cho, MC., Sung, K.C., Cho, E.J., Shin, J. (2022). Clinical Pharmacology of Antihypertensive Drugs. In: Ram, C.V.S., Teo, B.W.J., Wander, G.S. (eds) Hypertension and Cardiovascular Disease in Asia. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-030-95734-6_20

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  • DOI: https://doi.org/10.1007/978-3-030-95734-6_20

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-95733-9

  • Online ISBN: 978-3-030-95734-6

  • eBook Packages: MedicineMedicine (R0)

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