Abstract
Diuretics play a key role in hypertension management. These drugs are the least expensive of available antihypertensive agents. Therefore, diuretics are often utilised for initiation of antihypertensive therapy in low-income countries. In India, China and Japan, diuretics are most often used in combination with renin–angiotensin system inhibitors and calcium channel blockers (CCBs) and less often as monotherapy. The dosages of diuretics used in clinical practice are often lower than those recommended by the authorised guidelines. Physicians do this to avoid the side effects of diuretics. However, these side effects can be diagnosed and managed by the treating physicians. Mineralocorticoid receptor antagonists are the best option for add-on antihypertensive therapy in patients with resistant hypertension, but are underutilised due to the risk of hyperkalaemia and cost. Health providers in Asia need to look into ways in which all antihypertensive agents can be used more effectively to achieve effective blood pressure control.
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My grateful thanks to Mr. Ivor Dsouza for transcription and script reading without whom this would not have been possible.
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Kirpalani, A.L., Kirpalani, D.A. (2022). Diuretics for Hypertension in Asians. In: Ram, C.V.S., Teo, B.W.J., Wander, G.S. (eds) Hypertension and Cardiovascular Disease in Asia. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-030-95734-6_21
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DOI: https://doi.org/10.1007/978-3-030-95734-6_21
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