Abstract
Angiotensin receptor blockers (ARBs) are among the most widely used classes of antihypertensive drugs. In addition to their established efficacy and safety, ARBs are well tolerated and have a lower discontinuation rate than any other antihypertensive therapy. To further reduce cardiovascular risk, researchers are looking at multifunctional ARBs with actions beyond just inhibition of the renin–angiotensin system. Some of these additional properties/actions and their implications are discussed in this chapter. These ARBs may have additional actions on their own or may be combined with other molecules to provide further benefit. This has resulted in appearance of some new agents. Two of these, azilsartan and fimasartan, are discussed in detail. Recent studies have also identified newer actions of older agents in this class. Physicians also need to be aware of recalls that apply to some ARB products.
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Iyengar, S.S., Saleha, N. (2022). Newer Angiotensin Receptor Blockers. In: Ram, C.V.S., Teo, B.W.J., Wander, G.S. (eds) Hypertension and Cardiovascular Disease in Asia. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-030-95734-6_23
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DOI: https://doi.org/10.1007/978-3-030-95734-6_23
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